Journal of Translational Neurosciences

Haloperidol plus Promethazine for Psychosis-induced Aggression

Agitated or violent behaviour is prevalent in emergency services. Most of these incidents are due to severe psychiatric illness, but neurologic and metabolic issues may also be the underlying cause. The drugs used in such situations should ensure that the person becomes calm swiftly and safely. The combination haloperidol plus promethazine has long been used in developing countries, but NICE 2015 updated guidance now recommends this combination as one possible approach.

Gisele Huf