Recent studies estimate nearly half of the US population can access mobile medical applications (apps) on their smartphones. There are no systematic data available on apps focused on stroke survivors/caregivers. To identify apps (a) designed for stroke survivors/ caregivers, (b) dealing with a modifiable stroke risk factor (SRF), or (c) were developed for other purposes but could potentially be used by stroke survivors/caregivers. A systematic review of the medical apps in the US Apple iTunes store was conducted between August 2013 and January 2016 using 18 predefined inclusion/exclusion criteria. SRFs considered were: diabetes, hypertension, smoking, obesity, atrial fibrillation, and dyslipidemia.