Journal of Translational Neurosciences

Abstract

According to the ců�?ƐƐŝĮc�?�?Žn of the ŝn�?�?rn�?�?Žn�?ů headache society (ICHD), chronic migraine refers to �?�?�?�?n�?Ɛ with frequent headaches that are considered biologically migraine (Аmerican Headache Society, 2019). In migraine �?Ʃ�?cŬƐ�? the main role is played by successive stages of changes in vascular tone: spasm, �?ŝů�?�?Žn�? edema of vascular walls and periarterial �?ƐƐƵ�?Ɛ�? which determines the clinic of the disease (�?ƵůƐ�?�?nŐ pain that increases by physical �?c�?vŝ�?y�? nausea and/or vŽmŝ�?nŐ�? phone- and photophobia) (Yang Y., et al., 2016). A c�?�?r�?c�?�?rŝƐ�?c sign of the disease is the migraine aura in the form of transient neurological symptoms that precede a headache �?Ʃ�?cŬ